A friend of mine at work Wii-bowled last weekend with his wife and her Grandmother! She is 90-years-old and was an avid bowler. Since it is difficult for her to bowl these days they thought she might enjoy trying WiiSports Bowling out for size. First they got her to try out arm-chair bowling and by day two she was up and doing a full step through.
Very cool.
Also I found this article that is kind of fun to read. About a nursing home that bought a Wii for its residents.